Department of Orthopaedic Surgery, Yamaguchi University School of Medicine, 1-1-1 Minamikogushi, Ube, Yamaguchi, 755-8505, Japan,
Knee Surg Sports Traumatol Arthrosc. 2014 Nov;22(11):2614-7. doi: 10.1007/s00167-013-2460-9. Epub 2013 Mar 5.
This report describes a case of Staphylococcus aureus infection following open wedge high tibial osteotomy, which was successfully treated with by implant removal and replacement with antibiotic-impregnated calcium phosphate cement along with external fixation. The infection occurred 7 months after primary surgery and was treated by implant removal, debridement, external fixation, and application of vancomycin impregnated calcium phosphate cement to fill the defect. Subsequently, the infection resolved completely, and the osteotomy healed with no correction loss. Compared with conventional bone cement, calcium phosphate cement might be an optimal material for certain cases of infection after open wedge high tibial osteotomy because of its higher antibiotic retention, biocompatibility, osteoconductivity, and compatibility with heatlabile antibiotics.
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本报告描述了一例高位胫骨开放楔形截骨术后金黄色葡萄球菌感染的病例，通过取出植入物并用抗生素浸渍的磷酸钙骨水泥替代，并结合外固定架治疗，该感染成功治愈。感染发生在初次手术后 7 个月，通过取出植入物、清创、外固定和应用万古霉素浸渍的磷酸钙骨水泥填充缺损进行治疗。随后，感染完全消退，截骨愈合且无矫正丢失。与传统骨水泥相比，磷酸钙骨水泥可能是高位胫骨开放楔形截骨术后感染的一种理想材料，因为它具有更高的抗生素保留率、生物相容性、骨传导性和与热敏抗生素的兼容性。
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