Ryzhikov S B, Bliumenfel'd L A, Petrusevich Iu M, Tikhonov A N
Biofizika. 1990 Jan-Feb;35(1):141-2.
It has been shown that a fast increase in pH of myosin solution leads to ATP formation de novo from ADP and Pi (about one ATP molecule per one myosin molecule). The obligatory condition for ATP synthesis was that the value of pH 7.9-8.0 should be crossed in the course of pH-jump. The data obtained are explained in terms of the concept of conformational relaxation in enzyme catalysis.
已经表明,肌球蛋白溶液pH值的快速升高会导致由ADP和Pi重新合成ATP(大约每一个肌球蛋白分子产生一个ATP分子)。ATP合成的必要条件是在pH跃变过程中pH值应越过7.9 - 8.0。根据酶催化中构象弛豫的概念对所获得的数据进行了解释。