Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan,
Surg Today. 2014 Apr;44(4):633-9. doi: 10.1007/s00595-013-0535-3. Epub 2013 Mar 7.
The purpose of our study was to evaluate the efficacy of balloon-occluded retrograde transvenous obliteration (B-RTO) in patients after living donor liver transplantation (LDLT).
Five patients with gastric varices (GVx) and/or liver dysfunction who were treated with B-RTO from January 2001 to December 2007 were enrolled in this study (GVx, n = 2; liver dysfunction, n = 1; both, n = 2). The eradication rate of the GVx, portal vein hemodynamics and improvement of liver function were evaluated.
B-RTO was performed successfully, and the GVx disappeared or decreased markedly in all patients. Recurrence of GVx was not observed during the follow-up. Significantly increased portal vein inflow and improved liver function were observed in all patients.
B-RTO may be an effective treatment for patients after LDLT to prevent bleeding from GVx or to modulate portal vein inflow that is reduced by prolonged large portosystemic shunts.
本研究旨在评估球囊阻塞逆行经静脉闭塞术（B-RTO）在活体肝移植（LDLT）后的患者中的疗效。
本研究纳入了 2001 年 1 月至 2007 年 12 月期间接受 B-RTO 治疗的 5 例胃静脉曲张（GVx）和/或肝功能障碍患者（GVx，n=2；肝功能障碍，n=1；两者均有，n=2）。评估了 GVx 的消除率、门静脉血流动力学和肝功能的改善情况。
B-RTO 手术均成功完成，所有患者的 GVx 均明显消失或减少。在随访期间未观察到 GVx 复发。所有患者的门静脉流入均显著增加，肝功能得到改善。
B-RTO 可能是治疗 LDLT 后患者的有效方法，可预防 GVx 出血或调节因长时间大的门体分流导致的门静脉流入减少。
