Department of Surgery, Sirio Libanes Hospital, Sao Paulo, Brazil.
Ann Surg Oncol. 2013 May;20(5):1491-3. doi: 10.1245/s10434-013-2920-y. Epub 2013 Mar 7.
A new method for liver hypertrophy was recently introduced, the so-called associating liver partition and portal vein ligation for staged hepatectomy (ALPPS) procedure. We present a video of an ALPPS procedure with the use of pneumoperitoneum.
A 29-year-old woman with colon cancer and synchronous liver metastasis underwent a two-stage liver resection by the ALPPS technique because of an extremely small future liver remnant.
The first operation began with 30 min pneumoperitoneum. Anatomical resection of segment 2 was performed, followed by multiple enucleations on the left liver. The right portal vein was ligated and the liver partitioned. The abdominal cavity was partially closed, and a 10 mm trocar was left to create a pneumoperitoneum for additional 30 min. The patient had an adequate future liver remnant volume after 7 days, but she was not clinically fit for the second stage of therapy, so it was postponed. She was discharged on day 7 after surgery. The second stage took place 3 weeks later and consisted of an en-bloc right trisectionectomy extended to segment 1. The patient recovered and was discharged 9 days after second-stage surgery. Postoperative CT scan revealed an enlarged remnant liver.
The ALPPS procedure is a new revolutionary technique that permits R0 resection even in patients with massive liver metastasis. The use of pneumoperitoneum during the first stage is an easy tool that may prevent hard adhesions, allowing an easier second stage. This video may help oncological surgeons to perform and standardize this challenging procedure.
最近引入了一种新的肝肥大方法,即所谓的联合肝脏分割和门静脉结扎分期肝切除术(ALPPS)。我们展示了一段使用气腹的 ALPPS 手术视频。
一名 29 岁女性患有结肠癌和同步肝转移,由于未来肝残留量极小,她接受了两阶段肝切除术,采用 ALPPS 技术。
第一阶段手术开始时使用 30 分钟气腹。进行了第 2 段解剖性切除,随后在左肝进行了多次剜除。结扎右门静脉并进行肝脏分割。部分关闭腹腔,留下一个 10 毫米的 trocar 以创建额外的 30 分钟气腹。7 天后,患者的未来肝残留量足够,但她的临床状况不适合第二阶段治疗,因此被推迟。她在手术后第 7 天出院。第二阶段在 3 周后进行,包括右三叶切除术扩大到第 1 段的整块切除术。患者恢复良好,在第二阶段手术后 9 天出院。术后 CT 扫描显示残留肝脏增大。
ALPPS 手术是一种新的革命性技术,即使在大量肝转移患者中也能实现 R0 切除。在第一阶段使用气腹是一种简单的工具,可防止硬粘连,使第二阶段更容易进行。这段视频可能有助于肿瘤外科医生进行并规范这一具有挑战性的手术。