Blondon M, Le Gal G, Aujesky D, Righini M, Perrier A
Service de Médecine Interne Générale, Départment de Médicine Interne, Réhabilitation et Gériatrie, HUG 1211, Genève.
Rev Med Suisse. 2013 Feb 6;9(372):306-8, 310.
The usefulness of anticoagulation in patients with suspected non-massive pulmonary embolism (PE) is uncertain. We recently published a decision analysis model suggesting a benefit for preemptive anticoagulation in patients with an intermediate or high probability of PE, even with short diagnostic delays (0-3 h). In case of a low probability of PE, the decision to treat or not could partly rely on the expected diagnostic delay. Once the diagnosis is confirmed, achieving rapidly therapeutic anticoagulation levels decreases future thrombotic complications.
抗凝治疗对疑似非大面积肺栓塞（PE）患者的有效性尚不确定。我们最近发表了一个决策分析模型，表明即使诊断延迟较短（0 - 3小时），对于PE可能性为中度或高度的患者，抢先抗凝治疗有益。如果PE可能性较低，治疗与否的决策可能部分取决于预期的诊断延迟。一旦确诊，迅速达到治疗性抗凝水平可减少未来的血栓形成并发症。
