成纤维细胞生长因子 23 相关骨骼疾病。

FGF23 associated bone diseases.

机构信息

Institute of Metabolism and Endocrinology, the Second Xiangya Hospital, Central South University, Changsha, 410011, China.

出版信息

Front Med. 2013 Mar;7(1):65-80. doi: 10.1007/s11684-013-0254-6. Epub 2013 Mar 9.

DOI:10.1007/s11684-013-0254-6

PMID:23471660

Abstract

Recently, fibroblast growth factor 23 (FGF23) has sparked widespread interest because of its potential role in regulating phosphate and vitamin D metabolism. In this review, we summarized the FGF superfamily, the mechanism of FGF23 on phosphate and vitamin D metabolism, and the FGF23 related bone disease.

摘要

最近，成纤维细胞生长因子 23（FGF23）因其在调节磷酸盐和维生素 D 代谢中的潜在作用而引起广泛关注。在这篇综述中，我们总结了 FGF 超家族、FGF23 对磷酸盐和维生素 D 代谢的作用机制以及 FGF23 相关的骨骼疾病。