Department of Radiology, Kanagawa Cardiovascular and Respiratory Center, Yokohama, Japan.
Magn Reson Med Sci. 2013 Mar 25;12(1):1-9. doi: 10.2463/mrms.2012-0040. Epub 2013 Mar 11.
Pulmonary arterial hypertension (PAH) is a syndrome that results from restricted blood flow through the pulmonary arterial circulation, which leads to a pathological increase in pulmonary vascular resistance (PVR) and ultimately to right heart failure. The prognosis of patients with PAH has improved with the recent development of new medications. The need for new noninvasive diagnostic tools is increasing. Magnetic resonance (MR) imaging is the gold standard for assessing the right ventricle (RV). Its high degree of reproducibility makes it ideal for monitoring changes in RV parameters in response to therapy. MR imaging can also provide both anatomical and functional information about pulmonary hemodynamics. This article reviews the current status of MR imaging of the right side of the heart and pulmonary circulation in patients with PAH and other associated pulmonary diseases.
肺动脉高压（PAH）是一种综合征，由肺循环中血流受限引起，导致肺血管阻力（PVR）病理性增加，最终导致右心衰竭。随着新药物的研发，PAH 患者的预后得到了改善。对新的非侵入性诊断工具的需求正在增加。磁共振（MR）成像被认为是评估右心室（RV）的金标准。其高度的可重复性使其成为监测 RV 参数对治疗反应变化的理想选择。MR 成像还可以提供有关肺动脉高压和其他相关肺部疾病患者的肺血流动力学的解剖和功能信息。本文综述了 PAH 患者右心和肺循环的 MR 成像现状。
