Division of Internal Medicine, Department of Gastroenterology, University Hospital Rijeka, Rijeka, Croatia.
Gastroenterol Res Pract. 2013;2013:956149. doi: 10.1155/2013/956149. Epub 2013 Feb 14.
Introduction. Several European studies have reported an increase in the incidence rate of acute pancreatitis (AP). Therefore, we studied the incidence rate of AP in the North Adriatic Region in Croatia, as well as epidemiological analysis concerning etiology, age, gender, and severity of disease. Methods. We analyzed 922 patients with confirmed diagnosis of AP (history, clinical and laboratory findings, and imaging methods) admitted to our hospital during a ten-year period (2000-2009). Epidemiological analysis was carried out focusing on incidence, demographic data, and etiology, as well as severity of the disease based on the Ranson and APACHE II scores. Results. The incidence rate varied from 24 to 35/100 000 inhabitants annually. Mean age was 60 ± 16 years. There were 53% men and 47% women among the patients. Most frequent etiologies of AP were biliary stones in 60% and alcohol abuse in 19% of patients. According to the Ranson and APACHE II scores, pancreatitis was considered to be severe in 50% and 43% of the cases, respectively. Conclusion. In our region the incidence of AP was around 30 per 100,000 population per year during the ten-year period studied. The mean age at admission was 60 years and etiology was predominantly biliary. In our region, we have shown epidemiological characteristics of AP typical for Mediterranean countries.
简介。 几项欧洲研究报告称，急性胰腺炎（AP）的发病率有所增加。 因此，我们研究了克罗地亚北部亚得里亚海地区的 AP 发病率，以及病因，年龄，性别和疾病严重程度的流行病学分析。 方法。 我们分析了 922 名在我们医院确诊为 AP 的患者（病史，临床和实验室发现以及影像学方法），这些患者在十年间（2000-2009 年）住院。 我们针对发病率，人口统计学数据以及病因和根据 Ranson 和 APACHE II 评分的疾病严重程度进行了流行病学分析。 结果。 发病率从每年 24 至 35/100,000 居民不等。 平均年龄为 60 ± 16 岁。 患者中有 53％为男性，47％为女性。 AP 的最常见病因是胆石症，占 60％，酒精滥用占 19％。 根据 Ranson 和 APACHE II 评分，分别有 50％和 43％的胰腺炎被认为是严重的。 结论。 在我们的地区，在研究的十年期间，每年每 100,000 人口中有大约 30 例 AP。 入院时的平均年龄为 60 岁，病因主要是胆石症。 在我们的地区，我们已经显示出与地中海国家典型的 AP 流行病学特征。
