Armstrong J, Pomeroy M, Fennelly J J, Cahalane S
Department of Oncology, Children's Hospital, Dublin.
Ir J Med Sci. 1990 Feb;159(2):40-3. doi: 10.1007/BF02937246.
58 patients under the age of 14 years with acute lymphoblastic leukaemia were managed from 1971 to 1985. We analysed their overall survival from diagnosis to assess the prognostic significance of clinical and laboratory features present at diagnosis. Factors which were statistically significant included white blood count, platelet count, palpable lymph node enlargement, mediastinal widening on chest x-ray and palpable splenic enlargement. The purpose of this study was to identify that subset of patients which might have benefitted from more intensive treatment.
1971年至1985年期间，对58名14岁以下的急性淋巴细胞白血病患者进行了治疗。我们分析了他们从诊断开始的总生存期，以评估诊断时存在的临床和实验室特征的预后意义。具有统计学意义的因素包括白细胞计数、血小板计数、可触及的淋巴结肿大、胸部X线显示的纵隔增宽和可触及的脾肿大。本研究的目的是确定那些可能从更强化治疗中获益的患者亚组。
