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泛影葡胺(®)在粘连性肠梗阻治疗中的应用

[Use of Gastrografin(®) in the management of adhesion intestinal obstruction].

作者信息

Mora López Laura, Serra-Aracil Xavier, Llaquet Bayo Heura, Navarro Soto Salvador

机构信息

Servicio de Cirugía General y del Aparato Digestivo, Corporació Sanitària i Universitària Parc Taulí, Sabadell, Barcelona, España.

出版信息

Cir Esp. 2013 Jun-Jul;91(6):384-8. doi: 10.1016/j.ciresp.2012.10.011. Epub 2013 Mar 8.

DOI:10.1016/j.ciresp.2012.10.011
PMID:23477447
Abstract

BACKGROUND

Adhesions are the most important cause of intestinal obstruction. Approximately 25% of surgical admissions for acute abdominal conditions are due to intestinal obstruction. Better diagnostic and treatment methods of intestinal obstruction could potentially reduce mortality rate to 5-10%. Gastrografin(®) could contribute to this achieve this.

AIM

To present a protocol to treat adhesion intestinal obstruction with Gastrografin(®) that is safe, and allows shorter hospital stays and shorter time between admission and surgery.

MATERIAL AND METHODS

All patients with adhesion intestinal obstruction without symptoms of strangulation were treated with Gastrografin(®), intravenous fluids and nasogastric tube. Those in whom contrast reach the colon in 8, 12 or 24hours were considered to have partial obstruction, and were fed orally. If Gastrografin(®) failed in the following 24hours, a laparotomy was performed.

RESULTS

Out of a total of 211 episodes (164 patients), 170 episodes received contrast and in 142 cases Gastrografin(®) reached the colon (104 episodes at 8h, 11 at 12h, and 27 at 24h). A laparotomy was required in 28 patients because of failed treatment, and in another 5 for other causes.

CONCLUSIONS

A management protocol for adhesion intestinal obstruction with Gastrografin(®) is safe, reduces morbidity and mortality, and leads to a shorter hospital stay.

摘要

背景

粘连是肠梗阻最重要的病因。急性腹部疾病的外科住院患者中约25%是由肠梗阻引起的。更好的肠梗阻诊断和治疗方法有可能将死亡率降至5% - 10%。泛影葡胺(®)有助于实现这一目标。

目的

提出一种使用泛影葡胺(®)治疗粘连性肠梗阻的方案,该方案安全,可缩短住院时间以及入院至手术的间隔时间。

材料与方法

所有无绞窄症状的粘连性肠梗阻患者均接受泛影葡胺(®)、静脉输液和鼻胃管治疗。造影剂在8、12或24小时内到达结肠的患者被认为是部分梗阻,给予口服喂养。如果泛影葡胺(®)在接下来的24小时内治疗失败,则进行剖腹手术。

结果

在总共211例发作(164例患者)中,170例接受了造影剂检查,142例中泛影葡胺(®)到达结肠(8小时时104例,12小时时11例,24小时时27例)。28例患者因治疗失败需要进行剖腹手术,另外5例因其他原因进行手术。

结论

使用泛影葡胺(®)治疗粘连性肠梗阻的管理方案是安全的,可降低发病率和死亡率,并缩短住院时间。

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Cir Esp. 2013 Jun-Jul;91(6):384-8. doi: 10.1016/j.ciresp.2012.10.011. Epub 2013 Mar 8.
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