Spinale F G, Carabello B A, Crawford F A
Division of Cardiothoracic Surgery, Medical University of South Carolina, Charleston 29425.
J Appl Physiol (1985). 1990 Apr;68(4):1707-16. doi: 10.1152/jappl.1990.68.4.1707.
Right ventricular (RV) volumetric and morphological analysis is complicated by the trabeculations and geometric configuration of the RV chamber. To improve RV analysis, custom computer-aided design programs were employed to obtain RV volumes and three-dimensional models from biplane ventriculograms. Biplane RV ventriculograms were analyzed from 14 anesthetized dogs and 22 RV casts. Computed volumes were highly correlated with reference RV volumes (r = 0.98, n = 36, P less than 0.01) with a range of 5-73 ml. Three-dimensional wire-frame and solid models constructed from the ventriculographic images provided excellent detail and a new perspective in chamber shape. This modeling technique was then used to examine RV volumes, geometric conformation, and regional shortening in 10 pigs during inotropic stimulation and preload reduction. Changes in RV volumes, ejection fraction, and regional motion were detected as well as alterations in chamber conformation. In summary 1) computer-aided design offers an accurate and simplified means to compute RV volumes using basic microcomputer equipment, and 2) three-dimensional reconstruction provided a unique view of RV geometry and a means to examine regional RV function.
右心室（RV）的容积和形态分析因右心室腔的小梁结构和几何形态而变得复杂。为了改进右心室分析，采用了定制的计算机辅助设计程序，从双平面心室造影中获取右心室容积和三维模型。对14只麻醉犬和22个右心室铸型的双平面右心室造影进行了分析。计算得到的容积与右心室参考容积高度相关（r = 0.98，n = 36，P < 0.01），范围为5 - 73毫升。由心室造影图像构建的三维线框模型和实体模型提供了出色的细节，并为腔室形状提供了新的视角。然后，这种建模技术被用于研究10只猪在变力刺激和前负荷降低过程中的右心室容积、几何形态和局部缩短情况。检测到了右心室容积、射血分数和局部运动的变化以及腔室形态的改变。总之，1）计算机辅助设计提供了一种使用基本微机设备计算右心室容积的准确且简化的方法，2）三维重建提供了右心室几何形态的独特视角以及一种检查右心室局部功能的方法。
