Treviño Villarreal D C, López Guevara V, Ramírez López L E, Tijerina Sáenz A
Facultad de Salud Pública y Nutrición, Universidad Autónoma de Nuevo León, Monterrey, Nuevo León, México.
Nutr Hosp. 2012 Sep-Oct;27(5):1562-8. doi: 10.3305/nh.2012.27.5.5909.
Obesity is a disorder associated to an inappropriate food intake and psychological problems predisposing to complications such as metabolic syndrome (MS), which has been related to chronic stress due to hypercortisolism-mediated impairments of the hypothalamushypophysis-adrenal (HHA) axis activity.
To determine the relationship between serum cortisol and MS components, the food intake, and anxiety disorder in 8-12 years old obese children.
78 children, 40 with obesity and 38 with appropriate weight. The following serum and clinical indicators were assessed: cortisol, glucose, HDL-cholesterol (c-HDL) and triglycerides; anthropometrical and clinical indicators: weight, height, body mass index (BMI), waist circumference (WC) and blood pressure (BP); food intake: deficient or excessive consumption and intake of energy and nutrients; psychological indicator: anxiety.
There exists a significant relationship between cortisol level and the number of MS components in obese children (p < 0.05). When assessing the cortisol level against each one of these components, there were no significant differences. When analyzing the total sample, the cortisol level showed a negative relationship with c-HDL (r = -0.228, p = 0.045). We found a significant relationship between the cortisol level and excessive intake of foods of animal origin and sugars and with the subsets of fats and sugars (p < 0.05). There were no significant differences in energy or nutrients intake or anxiety in obese children.
There exists a relationship between the cortisol level and the number of MS components as well as with excessive intake of foods of animal origin, sugars, and fats in obese children.
肥胖是一种与不当食物摄入及心理问题相关的病症，易引发如代谢综合征（MS）等并发症，而代谢综合征与下丘脑 - 垂体 - 肾上腺（HHA）轴活动因高皮质醇血症介导受损所导致的慢性应激有关。
确定8至12岁肥胖儿童血清皮质醇与代谢综合征各组分、食物摄入量及焦虑症之间的关系。
78名儿童，40名肥胖儿童和38名体重正常儿童。评估以下血清和临床指标：皮质醇、葡萄糖、高密度脂蛋白胆固醇（c - HDL）和甘油三酯；人体测量和临床指标：体重、身高、体重指数（BMI）、腰围（WC）和血压（BP）；食物摄入量：能量和营养素的摄入不足或过量；心理指标：焦虑。
肥胖儿童的皮质醇水平与代谢综合征组分数量之间存在显著关系（p < 0.05）。当针对这些组分中的每一个评估皮质醇水平时，未发现显著差异。在分析整个样本时，皮质醇水平与c - HDL呈负相关（r = -0.228，p = 0.045）。我们发现皮质醇水平与动物源性食物和糖类的过量摄入以及脂肪和糖类亚组之间存在显著关系（p < 0.05）。肥胖儿童在能量或营养素摄入或焦虑方面没有显著差异。
肥胖儿童的皮质醇水平与代谢综合征组分数量以及动物源性食物、糖类和脂肪的过量摄入之间存在关联。
