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[在高岭土上通过氨酰腺苷酸参与同时合成肽和寡核苷酸]

[The simultaneous synthesis of peptides and oligonucleotides on kaolinite with the participation of aminoacyladenylates].

作者信息

Egofarova R Kh, Vasil'eva N V, Moiseeva L N, Otroshchenko V A, Pavlovskaia T E

出版信息

Izv Akad Nauk SSSR Biol. 1990 Jan-Feb(1):136-40.

PMID:2347997
Abstract

A simultaneous synthesis of peptides (2-5 residues) and oligonucleotides (3-9 residues) has been carried out on caolinite matrix using amino acids and aminoacyladenylates as substrates. The rate of oligomer synthesis on mineral surface is higher than that in solution. The mechanism of synthesis has been described. The data has been discussed in connection with abiogenesis of two major types of biopolymers, proteins and nucleic acids.

摘要

已使用氨基酸和氨酰腺苷酸作为底物,在高岭石基质上同时进行了肽(2 - 5个残基)和寡核苷酸(3 - 9个残基)的合成。在矿物表面上的低聚物合成速率高于在溶液中的合成速率。已描述了合成机制。已结合蛋白质和核酸这两种主要生物聚合物的无生源说对数据进行了讨论。

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