Brown G K
Department of Psychiatry, University of Pennsylvania, Philadelphia 19104.
J Abnorm Psychol. 1990 May;99(2):127-37. doi: 10.1037//0021-843x.99.2.127.
There is considerable controversy in the literature regarding the extent to which chronic pain and depression are associated and the possible causal relationship of such an association. The present study examines these issues with a sample of 243 patients diagnosed with rheumatoid arthritis (RA) who were mailed questionnaires for six waves of data collection. The results indicated that RA patients experience higher levels of depressive symptomatology than community samples. Using a two-latent-variable, cross-lagged design, covariance structural modeling was conducted on self-report measures of pain and depression over 6-month intervals. Results most strongly supported a causal model in which pain predicts depression during the last 12 months of the study.
关于慢性疼痛与抑郁之间的关联程度以及这种关联可能存在的因果关系，文献中存在相当大的争议。本研究以243名被诊断为类风湿性关节炎（RA）的患者为样本，通过邮寄问卷的方式进行了六轮数据收集，以此来探讨这些问题。结果表明，类风湿性关节炎患者的抑郁症状水平高于社区样本。采用双潜变量交叉滞后设计，对疼痛和抑郁的自我报告测量数据进行了为期6个月间隔的协方差结构建模。结果最有力地支持了一种因果模型，即在研究的最后12个月中，疼痛预示着抑郁。
