School of Nursing, University of Pennsylvania, Philadelphia, Pennsylvania, USA; Division of Endocrinology and Diabetes, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
J Diabetes. 2013 Dec;5(4):456-61. doi: 10.1111/1753-0407.12039. Epub 2013 May 28.
Population-based (PB) registries of type 1 diabetes mellitus (T1DM) in children have been essential in determining the geographic, racial, and temporal patterns of the disease. There is a paucity of PB data on the prevalence of type 1 and type 2 diabetes (T2DM) in youth.
The prevalence of diabetes in children was determined using a PB survey of the 628 schools in Philadelphia. Data obtained included type of diabetes, date of birth, race, gender, date of diagnosis, diabetes treatment, and most recent height and weight.
The survey was completed by nurses at 510 schools (81% of schools) representing 252,896 children (70% of children in Philadelphia). Prevalence (per 1000) was computed. The survey identified 492 cases (355 T1DM, 88 T2DM, 49 type unknown). The overall prevalence of T1DM was 1.58 (0.73 White, 0.56 African American, 0.50 Hispanic); of T2DM was 0.35 (0.03 White, 0.28 African American, 0.05 Hispanic). Mean age at diagnosis was 8.6 and 11.9 years for T1DM and T2DM, respectively. The prevalence of T1DM was higher in boys--T2DM was higher in girls. Of children with T2DM, 25% were treated with insulin. BMI was ≥95th percentile in 20% of children weighed (10% of T1DM, 57% of T2DM).
Although the Philadelphia Pediatric Diabetes Registry is the longest ongoing US registry of its kind, these are the first PB diabetes prevalence data of children in Philadelphia. PB studies in schools are able to capture children with diabetes who are diagnosed and treated in a variety of settings.
基于人群(PB)的 1 型糖尿病(T1DM)登记处对于确定疾病的地理、种族和时间模式至关重要。目前,关于青少年 1 型和 2 型糖尿病(T2DM)的 PB 数据很少。
通过对费城 628 所学校进行 PB 调查,确定儿童糖尿病的患病率。获得的数据包括糖尿病类型、出生日期、种族、性别、诊断日期、糖尿病治疗方法以及最近的身高和体重。
该调查由 510 所学校(占学校总数的 81%)的护士完成,共代表 252896 名儿童(费城儿童的 70%)。按每千人计算患病率。调查共发现 492 例病例(355 例 T1DM、88 例 T2DM、49 例类型不明)。T1DM 的总患病率为 1.58(白人 0.73、非裔美国人 0.56、西班牙裔 0.50);T2DM 的患病率为 0.35(白人 0.03、非裔美国人 0.28、西班牙裔 0.05)。T1DM 和 T2DM 的诊断年龄平均分别为 8.6 岁和 11.9 岁。T1DM 男孩的患病率较高,而 T2DM 女孩的患病率较高。在 T2DM 患儿中,有 25%接受胰岛素治疗。体重指数(BMI)≥第 95 百分位数的儿童占 20%(10%的 T1DM,57%的 T2DM)。
尽管费城儿科糖尿病登记处是美国同类登记处中持续时间最长的,但这是费城首次基于人群的儿童糖尿病患病率数据。学校的 PB 研究能够捕捉到在各种环境中诊断和治疗的糖尿病儿童。