Vattikuti Urology Institute, Henry Ford Health System, Detroit, MI 48202, USA.
BJU Int. 2013 Jul;112(2):224-30. doi: 10.1111/bju.12059. Epub 2013 Mar 11.
To determine trends in demographics and treatment for inpatient upper urinary tract calculi in the USA using a population-based cohort.
All patients with a primary or secondary diagnosis of kidney or ureteric calculus between 1999 and 2009 in the US Nationwide Inpatient Sample were extracted and weighted. Temporal trend analyses were used to determine trends in gender, race and age presentation, as well as utilization rates of interventions. Temporal trends were quantified using the estimated annual percent change (EAPC) using least squares linear regression analysis.
Overall, 2 109 455 patients were hospitalized with upper urinary tract calculi over the 11-year period. The majority of admissions were for ureteric calculi (63.4%). Admissions for renal calculus increased by 12.1% during the study period (EAPC + 0.92%, P = 0.039, 95% CI: 0.17-1.66), whilst discharges for ureteric calculus remained stable. A significant increase (25.4%) in hospitalizations for women was found (EAPC + 2.21%, P < 0.001, 95% CI: 1.40-3.03); by 2006, more women than men were admitted to hospital (95 953 vs. 94 556, respectively). There were significant increases in hospitalization for black, Hispanic and older patients. Significant changes in the use of all studied interventions were found except for ureteroscopy, extracorporeal shockwave lithotripsy and nephrectomy.
In this nationally representative sample of inpatient discharges, significant increases were found in admissions for renal compared with ureteric calculi, and for black, Hispanic and older patients. With regard to surgical intervention, the largest increase was found in the use of procedures for kidney calculi. Women now comprise the majority in the inpatient management of stone disease.
利用基于人群的队列研究,确定美国住院患者上尿路结石的人口统计学和治疗趋势。
从美国全国住院患者样本中提取并加权了 1999 年至 2009 年间所有原发性或继发性肾结石或输尿管结石患者的资料。采用时间趋势分析确定了性别、种族和年龄表现以及干预措施使用率的趋势。使用最小二乘线性回归分析,通过估计的年平均变化百分比(EAPC)来量化时间趋势。
在 11 年期间,共有 2109455 例患者因上尿路结石住院治疗。大多数住院患者为输尿管结石(63.4%)。研究期间,肾结石的住院人数增加了 12.1%(EAPC + 0.92%,P = 0.039,95%可信区间:0.17-1.66),而输尿管结石的出院人数保持稳定。女性的住院人数显著增加(25.4%)(EAPC + 2.21%,P < 0.001,95%可信区间:1.40-3.03);到 2006 年,女性入院人数超过男性(分别为 95953 例和 94556 例)。黑人、西班牙裔和老年患者的住院人数显著增加。除输尿管镜检查、体外冲击波碎石术和肾切除术外,所有研究干预措施的使用均发生显著变化。
在这个具有全国代表性的住院患者出院样本中,与输尿管结石相比,肾结石的入院人数以及黑人、西班牙裔和老年患者的入院人数显著增加。就手术干预而言,用于肾结石的程序使用量增加最多。女性目前在结石病的住院治疗中占多数。