Urology Unit, Cannizzaro Hospital, via Messina 829, Catania, Italy.
Anticancer Res. 2013 Mar;33(3):1195-9.
Magnetic resonance imaging (MRI) accuracy in prostate cancer (PCa) diagnosis in men submitted to saturation prostate biopsy (SPBx) was evaluated.
From June 2011 to December 2012, 78 patients (median 63 years) underwent repeat SPBx (median 28 cores). Multiparametric MRI using a 3 Tesla pelvic phased-array coil was performed before SPBx and lesions suspicious for PCa were submitted to additional targeted biopsies.
A T1c PCa was found in 32 (41%) cases. SPBx vs. MRI-suspicious targeted biopsy diagnosed 28 (87.5%) vs. 26 (81.2%) PCa missing four (12.5%) and six (18.8%) cancers localized in the anterior zone and in the lateral margin of the prostate, respectively; moreover, MRI diameter lesions correlated with PCa diagnosis and Gleason score (p<0.05).
Multiparametric MRI improved SPBx accuracy in diagnosing PCa of the anterior zone; moreover, suspicious areas >10 mm resulted as highly predictive of cancer (about 70% of the cases).
评估磁共振成像（MRI）在接受饱和前列腺活检（SPBx）的男性前列腺癌（PCa）诊断中的准确性。
2011 年 6 月至 2012 年 12 月，78 例患者（中位年龄 63 岁）接受重复 SPBx（中位 28 个核心）。在 SPBx 前进行多参数 MRI，使用 3T 盆腔相控阵线圈，对可疑 PCa 的病变进行额外的靶向活检。
32 例（41%）发现 T1c PCa。SPBx 与 MRI 可疑靶向活检诊断出 28 例（87.5%）和 26 例（81.2%）PCa，分别遗漏了 4 例（12.5%）和 6 例（18.8%）位于前列腺前区和侧缘的癌症；此外，MRI 直径病变与 PCa 诊断和 Gleason 评分相关（p<0.05）。
多参数 MRI 提高了 SPBx 诊断前区 PCa 的准确性；此外，可疑区域>10mm 高度提示癌症（约 70%的病例）。
