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发光双卡宾铱(III)配合物作为活细胞成像试剂。

Luminescent biscarbene iridium(III) complexes as living cell imaging reagents.

机构信息

Division of Nanobiomedicine, Suzhou Institute of Nano-Tech and Nano-Bionics, Chinese Academy of Sciences, 398 Ruoshui Road, Suzhou Industrial Park, Suzhou, Jiangsu 215123, PR China.

出版信息

Chem Commun (Camb). 2013 Apr 21;49(31):3230-2. doi: 10.1039/c3cc40845k. Epub 2013 Mar 13.

Abstract

Five iridium(III) complexes with two N-heterocyclic carbene (NHC) ligands and an ancillary ligand have been designed and successfully synthesized. With multicolor photoluminescence and low toxicity, these carbene complexes were tested, for the first time, as living cell imaging reagents and showed promise for application beyond the OLED (organic light emitting diode) area.

摘要

已经设计并成功合成了带有两个 N-杂环卡宾(NHC)配体和一个辅助配体的五种铱(III)配合物。这些卡宾配合物具有多色光致发光和低毒性,首次被测试为活细胞成像试剂,并有望在 OLED(有机发光二极管)领域之外得到应用。

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