Lou Zhong-Zi, Li Hong-Min, Yan Hong-Bin, Ni Xing-Wei, Jia Wan-Zhong
State Key Laboratory of Veterinary Etiological Biology, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou 730046, China.
Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi. 2012 Oct 30;30(5):401-5.
Through affecting on host innate and acquired immune responses, Echinococcus multilocularis orchestrates various interplays that are beneficial not only to facilitate its intrahepatic proliferation and maturation during life cycle, but also to limit pathological process in its intermediate host. This review reveals the role of the metacestode's immune-related molecules in modulating host responses and optimizing its own survival.
通过影响宿主的固有免疫和获得性免疫反应,多房棘球绦虫精心策划了各种相互作用,这些相互作用不仅有利于其在生命周期中促进肝内增殖和成熟,还能限制其中间宿主的病理过程。这篇综述揭示了原头蚴免疫相关分子在调节宿主反应和优化自身生存中的作用。