Ding Dan, Wang Jun-Yun
National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention, Laboratory of Parasite and Vector Biology, Ministry of Health, WHO Collaborating Centre for Malaria, Schistosomiasis and Filariasis, Shanghai 200025, China.
Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi. 2012 Oct 30;30(5):406-10.
Canine visceral leishmaniasis is caused by Leishmania infantum. Infected dogs, either symptomatic or asymptomatic, are considered as the major reservoirs for zoonotic visceral leishmaniasis. Accurate and rapid detection of canine leishmanial infection is crucial for control of human visceral leishmaniasis due to its role in the transmission of the infection to vectors. Various techniques based on parasitology, immunology and molecular biology have been studied and evaluated for detecting canine leishmanial infection. This article reviews the progress in techniques and methods for its diagnosis.
犬内脏利什曼病由婴儿利什曼原虫引起。受感染的犬,无论有无症状,都被视为动物源性内脏利什曼病的主要储存宿主。由于其在将感染传播给媒介方面的作用,准确快速地检测犬利什曼原虫感染对于控制人类内脏利什曼病至关重要。基于寄生虫学、免疫学和分子生物学的各种技术已被研究和评估用于检测犬利什曼原虫感染。本文综述了其诊断技术和方法的进展。