Institute of Nuclear Medicine, Catholic University of the Sacred Heart, Rome, Italy.
Clin Nucl Med. 2013 Aug;38(8):e333-5. doi: 10.1097/RLU.0b013e318279f389.
A 63-year-old woman underwent (18)F-FDG PET/CT searching for the cause of a fever of unknown origin. (18)F-FDG PET/CT incidentally detected a focal area of markedly increased radiopharmaceutical uptake in the right adrenal gland; this finding was suspicious for an adrenal malignancy or a functioning adenoma. Nevertheless, histology and laboratory data demonstrated the presence of a nonfunctioning adenoma. This case highlights that nonfunctioning adrenal adenomas should be considered as possible false-positive (18)F-FDG PET/CT findings for malignancy in the evaluation of adrenal incidentalomas, even when marked (18)F-FDG uptake is revealed.
一位 63 岁女性因不明原因发热接受 18F-FDG PET/CT 检查。18F-FDG PET/CT 偶然发现右侧肾上腺有放射性药物摄取明显增加的局灶性区域；这一发现提示肾上腺恶性肿瘤或功能性腺瘤的可能性。然而，组织学和实验室数据显示存在无功能腺瘤。本病例提示，在评估肾上腺意外瘤时，即使显示明显的 18F-FDG 摄取，无功能肾上腺腺瘤也应被视为恶性肿瘤的可能假阳性 18F-FDG PET/CT 结果。
