From the *Department of Nuclear Medicine, Oncology Institute of Southern Switzerland, Bellinzona, Switzerland; †Division of Endocrine and Metabolic Surgery; ‡Institute of Pathology; and §Institute of Nuclear Medicine, Università Cattolica del Sacro Cuore, Rome, Italy.
Clin Nucl Med. 2014 May;39(5):475-7. doi: 10.1097/RLU.0b013e31828e9752.
A 33-year old man underwent an F-FDG PET/CT searching for the cause of a fever of unknown origin. F-FDG PET/CT incidentally detected a focal area of markedly increased radiopharmaceutical uptake corresponding to a 2.5-cm nodule in the right adrenal gland. Laboratory data ruled out the presence of a functioning adrenal lesion. All these findings were suggestive of adrenal malignancy. After right adrenalectomy, histology showed a benign solitary fibrous tumor of the adrenal gland. This case highlights that benign solitary fibrous tumor should be considered as possible false-positive F-FDG PET/CT finding for malignancy in evaluating adrenal incidentalomas.
一位 33 岁男性因不明原因发热行 F-FDG PET/CT 检查。F-FDG PET/CT 偶然发现右侧肾上腺有一个 2.5 厘米大的结节,该处放射性摄取明显增加。实验室数据排除了功能性肾上腺病变的存在。所有这些发现均提示肾上腺恶性肿瘤。行右侧肾上腺切除术,组织学显示为良性孤立性纤维瘤。本病例提示,在评估肾上腺意外瘤时,良性孤立性纤维瘤应被视为 F-FDG PET/CT 恶性肿瘤假阳性的可能原因。