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2009-2011 年英国马属动物蹄叶炎的队列研究:577 例病例中疾病频率的估计和临床症状描述。

A cohort study of equine laminitis in Great Britain 2009-2011: estimation of disease frequency and description of clinical signs in 577 cases.

机构信息

Epidemiology Department, Centre for Preventive Medicine, Animal Health Trust, UK.

出版信息

Equine Vet J. 2013 Nov;45(6):681-7. doi: 10.1111/evj.12047. Epub 2013 Mar 12.

DOI:10.1111/evj.12047
PMID:23489181
Abstract

REASONS FOR PERFORMING STUDY

A previous systematic review highlighted a lack of good evidence regarding the frequency of equine laminitis in Great Britain.

OBJECTIVES

To estimate the frequency of veterinary-diagnosed active laminitis in the general horse population of Great Britain and to describe the clinical signs present in cases.

STUDY DESIGN

Prospective cohort study.

METHODS

Data on active episodes of equine laminitis were collected from veterinary practitioners.

RESULTS

The prevalence of veterinary-diagnosed active laminitis was 0.47% (95% confidence interval [CI] 0.42-0.52%) for the veterinary-attended population and 0.49% (95% CI 0.43-0.55%) for the veterinary-registered population, suggesting that active episodes of laminitis accounted for nearly one in 200 equine visits and occurred in nearly one in 200 horses registered with veterinary practices. The incidence of veterinary-diagnosed active laminitis was 0.5 cases per 100 horse-years at risk (95% CI 0.44-0.57). Laminitis occurred in all limbs, but most commonly affected the forelimbs bilaterally (53.5%, 95% CI 49.4-57.7%) and was most severe in the front feet. The most common clinical signs were increased digital pulses, difficulty turning and a short, stilted gait at walk.

CONCLUSIONS AND POTENTIAL RELEVANCE

The frequency of veterinary-diagnosed active laminitis was considerably lower than previously published estimates, which is probably due to differences in geographical setting, study period, case definition, study design and study populations.

摘要

研究目的

先前的系统评价强调了英国缺乏有关马属动物蹄叶炎发生频率的高质量证据。

目的

估计英国普通马群中兽医诊断的活动性蹄叶炎的频率,并描述病例中出现的临床症状。

研究设计

前瞻性队列研究。

方法

从兽医从业者那里收集关于活动性蹄叶炎发作的数据。

结果

兽医诊断的活动性蹄叶炎在接受兽医治疗的人群中的患病率为 0.47%(95%置信区间[CI],0.42-0.52%),在兽医登记的人群中的患病率为 0.49%(95%CI,0.43-0.55%),这表明活动性蹄叶炎发作几乎占每 200 次马就诊的近 1 次,在兽医诊所登记的每 200 匹马中就有近 1 匹发生。兽医诊断的活动性蹄叶炎的发病率为每 100 匹马年 0.5 例(95%CI,0.44-0.57)。蹄叶炎发生在所有四肢,但最常见的是双侧前肢(53.5%,95%CI,49.4-57.7%),前脚最严重。最常见的临床症状是数字脉搏增加、转身困难和行走时短而僵硬的步态。

结论和潜在相关性

兽医诊断的活动性蹄叶炎的频率明显低于先前发表的估计,这可能是由于地理位置、研究期间、病例定义、研究设计和研究人群的差异所致。

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