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[雌激素在儿童高反射型膀胱功能障碍和膀胱输尿管反流发病机制中的作用]

[The role of estrogens in the pathogenesis of bladder dysfunction of the hyperreflexia type and vesico-ureteral reflux in children].

作者信息

Derzhavin V M, Vishnevskiĭ E L, Abdurakhmanov Kh I, Mironov A V

出版信息

Pediatriia. 1990(2):10-4.

PMID:2349032
Abstract

Patients with the uninhibited urinary bladder of the hyperreflexia type and the vesicoureteral reflux were subjected to multimodality examinations which included excretory urography, retrograde cystometry, cystography, profilometry of the ureterovesical anastomosis, cytologic investigation of estrogenic saturation, determination of the concentration of follicle-stimulating hormone of the pituitary and estradiol by means of radioimmunoassay. As many as 56 girls aged 4 to 15 years underwent examination. It has been demonstrated that dysfunction of the urinary bladder of the hyperreflexia type is of crucial role as an active mechanism of extra-vesicalization of the intra-vesical part of the ureter, associated with its antireflux function distress.

摘要

对患有反射亢进型无抑制性膀胱和膀胱输尿管反流的患者进行了多模态检查,包括排泄性尿路造影、逆行膀胱测压、膀胱造影、输尿管膀胱吻合术轮廓测量、雌激素饱和度细胞学研究、通过放射免疫测定法测定垂体促卵泡激素和雌二醇的浓度。共有56名4至15岁的女孩接受了检查。结果表明,反射亢进型膀胱功能障碍作为输尿管膀胱内部分膀胱外移位的一种积极机制,与其抗反流功能受损密切相关,起着至关重要的作用。

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Pediatriia. 1990(2):10-4.
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