Goolden A W, Mclaughlin J E, Valentine A R, Pease C
Department of Histopathology, Royal Free Hospital, London, UK.
Postgrad Med J. 1990 Feb;66(772):127-9. doi: 10.1136/pgmj.66.772.127.
A woman aged 52 was treated with radioactive iodine for a papillary carcinoma of the thyroid. Four years later she developed signs and symptoms of an intracranial space occupying lesion. A computed tomographic scan showed a mass in the right posterior frontal region. Although she was suspected of having metastatic disease a definite diagnosis was not established until she died 6 months later when post-mortem examination confirmed that she had a cerebral metastasis from a papillary carcinoma of the thyroid. There was no evidence of metastatic disease elsewhere in the body. Cerebral metastases from papillary carcinoma of the thyroid are uncommon but may occur in patients who have metastases in bones or lungs. A search of the literature has revealed only two patients with solitary cerebral metastases.
一名52岁女性因甲状腺乳头状癌接受放射性碘治疗。四年后，她出现了颅内占位性病变的体征和症状。计算机断层扫描显示右后额叶区域有一个肿块。尽管怀疑她患有转移性疾病，但直到6个月后她去世时才确诊，尸检证实她患有甲状腺乳头状癌的脑转移。身体其他部位没有转移性疾病的证据。甲状腺乳头状癌的脑转移并不常见，但可能发生在有骨或肺转移的患者中。文献检索仅发现两名患有孤立性脑转移的患者。
