Fletcher Joel G, Krueger William R, Hough David M, Huprich James E, Fidler Jeff L, Wang Jia, Shiung Maria M, Harmsen W Scott, Grant Katharine L, McCollough Cynthia H
Departments of Radiology, Mayo Clinic, Rochester, MN 55905, USA.
J Comput Assist Tomogr. 2013 Mar-Apr;37(2):203-11. doi: 10.1097/RCT.0b013e31827e0e93.
The objective of this study was to determine the effect of Sinogram-Affirmed Iterative Reconstruction (SAFIRE) on radiological detection, diagnostic confidence, and image quality at half-dose, contrast-enhanced abdominopelvic computed tomography.
Forty dual-source examinations were reconstructed using routine-dose with filtered back projection, half-dose filtered back projection, and half-dose SAFIRE. Three radiologists detected lesions in abdominopelvic organs, reporting findings of potential medical significance, diagnostic confidence, and image quality.
There was greater than 78% concordance between full- and half-dose images ± SAFIRE, and no difference in the detection of lesions within organs between half-dose images ± SAFIRE (P = 0.22 - 1.0). Detection of potentially important findings varied by reader, but not between dose/reconstruction methods. Diagnostic confidence varied widely (P < 0.001 to P > 0.91). Sinogram-Affirmed Iterative Reconstruction significantly improved image quality in the pelvis (P ≤ 0.04).
Half-dose images ± SAFIRE had organ-specific detections similar to routine-dose images. Sinogram-Affirmed Iterative Reconstruction improved image quality in the pelvis, but diagnostic confidence and image quality scores in the abdomen depended on the reader.
本研究的目的是确定正弦图确认迭代重建（SAFIRE）对腹部盆腔增强CT半剂量扫描时的影像学检测、诊断信心及图像质量的影响。
40例双源CT检查采用常规剂量滤波反投影、半剂量滤波反投影和半剂量SAFIRE进行重建。三名放射科医生对腹部盆腔器官中的病变进行检测，并报告具有潜在医学意义的发现、诊断信心及图像质量。
全剂量图像与半剂量图像±SAFIRE之间的一致性超过78%，半剂量图像±SAFIRE之间在器官内病变的检测上无差异（P = 0.22 - 1.0）。对潜在重要发现的检测因阅片者而异，但在剂量/重建方法之间无差异。诊断信心差异很大（P < 0.001至P > 0.91）。正弦图确认迭代重建显著改善了盆腔的图像质量（P ≤ 0.04）。
半剂量图像±SAFIRE在器官特异性检测方面与常规剂量图像相似。正弦图确认迭代重建改善了盆腔的图像质量，但腹部的诊断信心和图像质量评分取决于阅片者。
