Hwang Hye Jeon, Seo Joon Beom, Lee Hyun Joo, Lee Sang Min, Kim Eun Young, Oh Sang Young, Kim Ji-Eun
Department of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.
J Comput Assist Tomogr. 2013 Jul-Aug;37(4):610-7. doi: 10.1097/RCT.0b013e31828f4dae.
This study aimed to determine optimal strength of sinogram-affirmed iterative reconstruction (SAFIRE) and to evaluate image quality (IQ) of low-dose chest computed tomography (LDCT) using SAFIRE compared with iterative reconstruction in image space (IRIS) and filtered back projection (FBP).
Thirty patients underwent LDCT. Computed tomography (CT) was reconstructed using 5 strengths of SAFIRE (S1-S5), IRIS, and FBP. Objective noise of CT was measured. Two radiologists evaluated CT for subjective IQ, beam-hardening artifacts, and overall IQ.
Measured noise was highest in FBP, followed by S1, S2, S3, IRIS, S4, and S5. S2 and S3 demonstrated significantly higher overall IQ scores than the other strengths (P < 0.05). Overall IQ and beam-hardening artifacts of S2 and S3 were significantly better than those in FBP and IRIS (P < 0.001).
S2 or S3 strengths of SAFIRE can be used practically in clinical routines and may have more potential than IRIS and FBP for LDCT with improved IQ.
本研究旨在确定正弦图确认迭代重建（SAFIRE）的最佳强度，并评估使用SAFIRE的低剂量胸部计算机断层扫描（LDCT）的图像质量（IQ），并与图像空间迭代重建（IRIS）和滤波反投影（FBP）进行比较。
30例患者接受了LDCT检查。使用5种强度的SAFIRE（S1 - S5）、IRIS和FBP对计算机断层扫描（CT）进行重建。测量CT的客观噪声。两名放射科医生对CT的主观IQ、束硬化伪影和整体IQ进行评估。
测量的噪声在FBP中最高，其次是S1、S2、S3、IRIS、S4和S5。S2和S3的整体IQ得分明显高于其他强度（P < 0.05）。S2和S3的整体IQ和束硬化伪影明显优于FBP和IRIS（P < 0.001）。
SAFIRE的S2或S3强度可实际应用于临床常规，对于LDCT，在改善IQ方面可能比IRIS和FBP具有更大潜力。
