School of Pharmacy, University College Cork, Cork, Ireland.
Int J Clin Pharm. 2013 Jun;35(3):439-46. doi: 10.1007/s11096-013-9760-5. Epub 2013 Mar 15.
Although preventable, venous thromboembolism remains a common cause of hospital acquired morbidity and mortality. Guidelines, such as the one produced by the American College of Chest Physicians (ACCP), are aimed at reducing hospital associated venous thromboemboli. Unfortunately the majority of studies have revealed inadequate adherence to these guidelines.
The objective of this study was to evaluate the use of venous thromboembolism prophylaxis at Cork University Hospital.
Cork University Hospital, Wilton, Cork, Ireland.
Data from the patient's chart, drug kardex and laboratory results were recorded during April 2010. A Caprini score, a venous thromboembolism risk factor assessment tool, was subsequently calculated for each patient based on data collected. Appropriate prophylaxis was determined after examining data collected, Caprini score and prophylactic regime according to the ACCP 8th edition guidelines.
Primary outcome was to analyse adherence to VTE prophylaxis guidelines.
A total of 394 patients met the inclusion criteria and were reviewed, of which, 60% (n = 236) were medical and 37% (n = 146) were surgical patients. In total 63% of patients received some form of venous thromboembolism prophylaxis. Furthermore, 54% of medical and 76% of surgical patients received prophylaxis. However only 37% of the patients studied received appropriate thromboprophylaxis according to the ACCP 8th edition guidelines (Geerts et al. in chest 133(6 Suppl):381S-453S, 2008). Additionally 51% of surgical and 27% of medical patients received appropriate prophylaxis.
Data collected from Cork University Hospital revealed poor adherence to international venous thromboembolism prophylaxis guidelines. As stated in the ACCP 8th edition guidelines, every hospital should develop a formal strategy for venous thromboembolism prevention (Geerts et al. in chest 133(6 Suppl):381S-453S, 2008). In order to improve adherence to guidelines, Cork University Hospital should develop, implement and re-evaluate a specific protocol for venous thromboembolism prophylaxis.
尽管可以预防，但静脉血栓栓塞仍然是医院获得发病率和死亡率的常见原因。指南，如美国胸科医师学会（ACCP）制定的指南，旨在减少医院相关的静脉血栓栓塞。不幸的是，大多数研究表明，这些指南的遵守情况并不理想。
本研究旨在评估科克大学医院使用静脉血栓栓塞预防措施的情况。
爱尔兰科克市威尔顿的科克大学医院。
在 2010 年 4 月期间，从患者的病历、药物卡片和实验室结果中记录数据。随后，根据收集到的数据，为每位患者计算 Caprini 评分，这是一种静脉血栓栓塞风险因素评估工具。根据收集到的数据、Caprini 评分和预防方案，按照 ACCP 第 8 版指南确定适当的预防措施。
主要结果是分析对静脉血栓栓塞预防指南的遵守情况。
共有 394 名符合纳入标准的患者进行了回顾性分析，其中 60%（n=236）为内科患者，37%（n=146）为外科患者。共有 63%的患者接受了某种形式的静脉血栓栓塞预防措施。此外，54%的内科患者和 76%的外科患者接受了预防措施。然而，根据 ACCP 第 8 版指南，只有 37%的患者接受了适当的血栓预防治疗（Geerts 等人，在胸部 133（6 补充）：381S-453S，2008）。此外，51%的外科患者和 27%的内科患者接受了适当的预防措施。
从科克大学医院收集的数据显示，国际静脉血栓栓塞预防指南的遵守情况不佳。如 ACCP 第 8 版指南所述，每个医院都应制定预防静脉血栓栓塞的正式策略（Geerts 等人，在胸部 133（6 补充）：381S-453S，2008）。为了提高对指南的遵守程度，科克大学医院应制定、实施和重新评估具体的静脉血栓栓塞预防方案。
