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[经肠胃外途径给予除草剂泽津S - 40后发育过程中实验大鼠身体的急性变化。I. LD50的测定及其他生化结果]

[Acute changes in the body of laboratory rats during development after the parenteral administration of the herbicide Zeazin S-40. I. Determination of LD50 and other biochemical findings].

作者信息

Trojanová M, Mourek J

机构信息

Fyziologický ústav fakulty vseobecného lékarství Univerzity Karlovy, Praha.

出版信息

Sb Lek. 1990 Mar;92(2-3):92-6.

PMID:2349447
Abstract

On laboratory rats of different age the effect of the acute intraperitoneal administration of the herbicide Zeazin S-40, 570 mg.kg-1 was investigated. The dose was derived after assessment of LD50 i. p. It was revealed that this substance causes during the first hour after introduction into the organism a response in the internal environment manifested among others by changes in the serum levels of glucose, lactate and triacylglycerols.

摘要

对不同年龄的实验大鼠进行了腹腔注射除草剂Zeazin S - 40(570毫克/千克)的急性给药效果研究。该剂量是在评估腹腔注射半数致死量后确定的。结果发现,该物质在进入机体后的第一小时内会引起内环境的反应,表现为血清葡萄糖、乳酸和三酰甘油水平的变化等。

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