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侧流香烟烟雾与心脏自主神经调节

Sidestream cigarette smoke and cardiac autonomic regulation.

作者信息

Valenti Vitor E, Vanderlei Luiz Carlos M, Ferreira Celso, Fonseca Fernando L A, Oliveira Fernando R, Sousa Fernando H, Rodrigues Luciano M, Monteiro Carlos B M, Adami Fernando, Wajnsztejn Rubens, de Abreu Luiz Carlos

机构信息

Department of Speech Language and Hearing therapy, Faculty of Philosophy and Sciences, UNESP, Av, Higyno Muzzi Filho, 737, Marilia, SP 17,525-900, Brazil.

出版信息

Int Arch Med. 2013 Mar 7;6(1):11. doi: 10.1186/1755-7682-6-11.

Abstract

BACKGROUND

The literature has already demonstrated that cigarette influences the cardiovascular system. In this study, we performed a literature review in order to investigate the relationship between sidestream cigarette smoke (SSCS) and cardiac autonomic regulation.

METHODS

Searches were performed on Medline, SciELO, Lilacs and Cochrane databases using the crossing between the key-words: "cigarette smoking", "autonomic nervous system", "air pollution" and "heart rate variability".

RESULTS

The selected studies indicated that SSCS exposure affects the sympathetic and parasympathetic responses to changes in arterial blood pressure. Moreover, heart rate responses to environmental tobacco smoke are increased in smokers compared to non-smokers. The mechanism involved on this process suggest increased oxidative stress in brainstem areas that regulate the cardiovascular system.

CONCLUSION

Further studies are necessary to add new elements in the literature to improve new therapies to treat cardiovascular disorders in subjects exposed to sidestream cigarette smoke.

摘要

背景

文献已经证明香烟会影响心血管系统。在本研究中,我们进行了文献综述,以调查侧流香烟烟雾(SSCS)与心脏自主调节之间的关系。

方法

使用关键词“吸烟”“自主神经系统”“空气污染”和“心率变异性”的交叉组合,在Medline、SciELO、Lilacs和Cochrane数据库中进行检索。

结果

所选研究表明,接触SSCS会影响对动脉血压变化的交感和副交感反应。此外,与不吸烟者相比,吸烟者对环境烟草烟雾的心率反应会增加。这一过程涉及的机制表明,调节心血管系统的脑干区域氧化应激增加。

结论

有必要进行进一步研究,为文献增添新内容,以改进针对接触侧流香烟烟雾的受试者治疗心血管疾病的新疗法。

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本文引用的文献

1
CaMK4 Gene Deletion Induces Hypertension.CaMK4 基因缺失导致高血压。
J Am Heart Assoc. 2012 Aug;1(4):e001081. doi: 10.1161/JAHA.112.001081. Epub 2012 Aug 24.
5
[Geometric index of heart rate variability in chronic obstructive pulmonary disease].[慢性阻塞性肺疾病中心率变异性的几何指数]
Rev Port Pneumol. 2011 Nov-Dec;17(6):260-5. doi: 10.1016/j.rppneu.2011.06.007. Epub 2011 Sep 14.
7
Sidestream tobacco smoke is a male germ cell mutagen.侧流烟草烟雾是一种雄性生殖细胞诱变剂。
Proc Natl Acad Sci U S A. 2011 Aug 2;108(31):12811-4. doi: 10.1073/pnas.1106896108. Epub 2011 Jul 18.

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