Fisher K S, Zamboni W A, Ross D S
Department of Surgery, Southern Illinois University School of Medicine, Springfield 62794-9230.
Am Surg. 1990 Jun;56(6):339-42.
A retrospective study was performed to evaluate and compare preoperative computed tomography (CT) scanning with less expensive tests that are used to identify hepatic metastases in patients with colorectal carcinoma. Thirty-three patients treated for colorectal carcinoma from January 1985 to December 1986 had preoperative CT scans performed as well as serum levels of lactose dehydrogenase (LDH), and carcinoembryonic antigen (CEA) measured. All patients underwent intraoperative evaluation of the liver. Only one patient had metastases found by CT exam that was not apparent at laparotomy. The sensitivity and specificity of the CT scan for detecting hepatic metastases were 1.00 and 0.96, respectively. The sensitivity and specificity of elevations in LDH or CEA when used in combination for detecting liver involvement was 1.00 and 0.54, respectively. Although the CT scan is effective in detecting hepatic metastases in patients with colorectal carcinoma we found that its routine use is unnecessary and expensive.
进行了一项回顾性研究,以评估和比较术前计算机断层扫描(CT)与用于识别结直肠癌患者肝转移的成本较低的检查。1985年1月至1986年12月期间接受结直肠癌治疗的33例患者进行了术前CT扫描,并检测了血清乳酸脱氢酶(LDH)和癌胚抗原(CEA)水平。所有患者均接受了肝脏的术中评估。只有1例患者通过CT检查发现有转移,而在剖腹手术中未发现。CT扫描检测肝转移的敏感性和特异性分别为1.00和0.96。联合使用LDH或CEA升高检测肝脏受累的敏感性和特异性分别为1.00和0.54。尽管CT扫描在检测结直肠癌患者的肝转移方面有效,但我们发现常规使用它既不必要又昂贵。