Department of Chemistry, University of Nebraska-Lincoln, Lincoln, NE 68588, USA.
Chem Commun (Camb). 2013 Apr 28;49(33):3422-4. doi: 10.1039/c3cc41281d.
We report a reagentless and reusable "signal-on" electrochemical DNA sensor that utilizes oligo-thymine as a flexible spacer. This sensor design is sensitive, specific, and selective; it is potentially generalizable for detection of a wide range of biomedical-relevant nucleic acid sequences.
我们报告了一种无试剂且可重复使用的“信号开启”电化学 DNA 传感器,该传感器利用寡胸腺嘧啶作为灵活的间隔物。该传感器设计具有灵敏度高、特异性强和选择性好的特点;它有可能推广应用于检测广泛的与生物医学相关的核酸序列。