Change of liver function during adaptation of man to northern conditions.

The liver is known to play a central part in carrying out the main phases of intermediate metabolism, in supplying the other organs and tissues with structure and energy substances. The investigations on the liver function of man in the process of organism adaptation to a variety of factors in northern regions are practically non-existent. This article has as its purpose a combined clinical and biochemical investigation of the main functions of the liver in people with various length of stay in extreme northern regions. The analysis of changes in the indices of the basic liver functions in practically healthy people during the process of adaptation to the extreme environmental conditions of the North show, that with a short-term adaptation these shifts were generally of a temporary character, whereas with a long-term adaptation of the newcomers there were relatively permanent changes in a number of indices.