Gomes O M, Conceicão D S, Nogueira D, Tsuzuky S, Bittencourt D, Zerbini E J
J Thorac Cardiovasc Surg. 1975 Apr;69(4):606-14.
A new bubble oxygenator has been developed. Its main advantage is that the dimensions of the oxygenating chamber can be varied. Thus, the capacity for oxygenation may be adapted to different patients. It was used in 2,700 open-heart operations performed at the Institut do Coracão, Faculdade de Medicina, Universidade de São Paulo, between January, 1971, and December, 1973. A group of 50 patients were subjected to more detailed studies. We found that the average hemolysis was 38.67 mg. per cent with a mean perfusion duration of 69 minutes, 38 seconds. Fibrinogen and platelet concentrations decreased by 14 and 25 per cent, respectively. The pH, PcO2, PO2, and base excess before and after cardiopulmonary bypass ranged within normal levels, and oxygenation (PO2) was always satisfactory.
一种新型鼓泡式氧合器已研制成功。其主要优点是氧合室的尺寸可以改变。因此,氧合能力可适用于不同患者。1971年1月至1973年12月期间,它被用于圣保罗大学医学院心脏研究所进行的2700例心脏直视手术。对一组50例患者进行了更详细的研究。我们发现,平均溶血率为38.67毫克%,平均灌注持续时间为69分38秒。纤维蛋白原和血小板浓度分别下降了14%和25%。体外循环前后的pH值、二氧化碳分压、氧分压和碱剩余均在正常范围内,且氧合(氧分压)始终令人满意。