Kábrt J, Masek Z, Svacina S, Koubková H, Sonka J
III. interní katedra fakulty vseobecného lékarství Univerzity Karlovy, Praha.
Cas Lek Cesk. 1990 May 4;129(18):558-61.
The authors investigated 38 obese patients with a BMI above 35. The patients were divided into four groups. The first three groups were on a strict reducing diet, which differed as to the energy values (1.38 MJ to 2.75 MJ) and the amount of protein (5.58 g N to 17.91 g N) per 24 hours. The fourth group fasted. In the course of 16 days metabolic balances were made and the energy output at rest was assessed by indirect calorimetry. In all groups the body weight declined markedly on average by 8.2 to 10.5 kg. The energy consumption at rest declined only during the complete fast. The fasting patients were in a negative nitrogen balance. The nitrogen balance was positive in the patients who were given 11.2 g N and 17.91 g N/24 hours. In all groups the fat utilization increased and the sugar utilization declined. The protein catabolism declined markedly only in the fasting patients. It may be summarized that the low-energy protein diet is, as compared with the fast, a more physiological way to achieve weight reduction, in particular because despite weight reduction a positive nitrogen balance is achieved.
作者对38名BMI高于35的肥胖患者进行了研究。这些患者被分为四组。前三组采用严格的节食方案，每组每天的能量值（1.38兆焦耳至2.75兆焦耳）和蛋白质量（5.58克氮至17.91克氮）有所不同。第四组进行禁食。在16天的过程中进行了代谢平衡测定，并通过间接测热法评估静息能量输出。所有组的体重平均显著下降了8.2至10.5千克。只有在完全禁食期间，静息能量消耗才会下降。禁食的患者处于负氮平衡。每天摄入11.2克氮和17.91克氮的患者氮平衡为正。所有组的脂肪利用率均增加，糖利用率均下降。只有禁食的患者蛋白质分解代谢显著下降。可以总结为，与禁食相比，低能量蛋白质饮食是一种更符合生理的减肥方式，特别是因为尽管体重减轻，但仍能实现正氮平衡。
