Joint Shantou International Eye Center, Shantou University and the Chinese University of Hong Kong, Shantou, China.
Retina. 2013 Jun;33(6):1258-62. doi: 10.1097/IAE.0b013e31827b63ba.
To investigate the structural features of outer retinal atrophy secondary to closed globe trauma and their correlation with visual prognosis, using spectral-domain optical coherence tomography (OCT).
In this retrospective study, patients with outer retinal atrophy secondary to closed globe trauma were examined with Topcon 3D OCT-1000. The foveal thickness was measured. The severity of outer retinal atrophy was graded into three levels: disruption of inner/outer segment layer, reduced thickness of outer nuclear layer, and disappearance of outer nuclear layer. Cases with >180 days of follow-up were included. The correlations between OCT features and best-corrected visual acuity at the last follow-up were analyzed.
Overall, 52 eyes of 52 patients were included, with mean follow-up of 286 ± 200 days. Spectral-domain OCT revealed disruption of the inner/outer segment layer with atrophy of outer nuclear layer and disorganization of inner retina in severe cases. The final best-corrected visual acuity significantly correlated with foveal thickness (r = -0.813; P < 0.001) and the grade of outer retinal atrophy (r = 0.796; P < 0.001).
Spectral-domain OCT revealed disruption of the inner/outer segment layer and atrophy of outer nuclear layer in cases of commotio retinae. Foveal thickness and grade of outer retinal atrophy were predictors for final visual outcome in these cases.
利用频域光相干断层扫描（OCT）研究闭合性眼球外伤后所致的外层视网膜萎缩的结构特征及其与视觉预后的相关性。
本回顾性研究纳入了使用 Topcon 3D OCT-1000 检查的闭合性眼球外伤后出现外层视网膜萎缩的患者。测量了黄斑中心凹厚度。将外层视网膜萎缩的严重程度分为 3 个等级：内/外节层中断、外核层厚度变薄和外核层消失。纳入随访时间超过 180 天的病例。分析 OCT 特征与末次随访时最佳矫正视力之间的相关性。
共有 52 例（52 只眼）患者纳入研究，平均随访时间为 286±200 天。频域 OCT 显示严重病例中存在内/外节层中断、外核层萎缩和内层视网膜排列紊乱。最终最佳矫正视力与黄斑中心凹厚度（r=-0.813；P<0.001）和外层视网膜萎缩程度（r=0.796；P<0.001）显著相关。
频域 OCT 显示了震荡性视网膜病变病例中的内/外节层中断和外核层萎缩。黄斑中心凹厚度和外层视网膜萎缩程度是这些病例最终视觉预后的预测指标。
