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玻璃体内切除联合曲安奈德辅助治疗与内界膜剥除治疗高度近视黄斑孔视网膜脱离的疗效比较。

Efficacy of vitrectomy with triamcinolone assistance versus internal limiting membrane peeling for highly myopic macular hole retinal detachment.

机构信息

Shaanxi Ophthalmic Medical Center, Xi'an No.4 Hospital, Affiliated Guangren Hospital, School of Medicine, Xi'an Jiaotong, University, Xi'an, China.

出版信息

Retina. 2013 Jun;33(6):1151-7. doi: 10.1097/IAE.0b013e31827b6422.

DOI:10.1097/IAE.0b013e31827b6422
PMID:23508079
Abstract

PURPOSE

To compare the outcomes of pars plana vitrectomy (PPV) with or without the adjuvant surgical procedures: triamcinolone acetonide (TA) assistance and/or internal limiting membrane (ILM) peeling for the treatment of highly myopic macular hole retinal detachment (MHRD).

DESIGN

Case-control study.

METHODS

Pars plana vitrectomy combined with 2 kinds of adjuvant surgical procedures were used on 96 highly myopic eyes with MHRD. These eyes were assigned to 4 groups randomly: Group 1, non-TA-assisted PPV and without ILM peeling; Group 2, non-TA-assisted PPV with ILM peeling; Group 3, TA-assisted PPV and without ILM peeling; Group 4, TA-assisted PPV with ILM peeling. Anatomical reattachment of the retina, macular hole closure, and best-corrected visual acuity were measured.

RESULTS

The rates of both retinal reattachment and macular hole closure were higher in Group 2 (84.0 and 44.0%) and Group 3 (80.8 and 46.2%) than Group 1 (73.9 and 17.4%); however, there were no differences between Group 2 and Group 3 (P > 0.05). The rates of macular hole closure were extremely low in Group 1 and also in eyes with extreme long axial lengths (≥29.0 mm), "severe" chorioretinal atrophy, and posterior staphyloma.

CONCLUSION

Pars plana vitrectomy with either TA assistance or ILM peeling was effective for the treatment of highly myopic MHRD. If you peel the ILM, adding TA does not affect closure rates; and if TA is used to visualize the vitreous, ILM peeling may not be necessary in MHRD. There was a lower anatomical success rate in MHRD with extreme long axial lengths, severe chorioretinal atrophy, and posterior staphyloma.

摘要

目的

比较经睫状体平坦部玻璃体切除术(PPV)联合或不联合辅助手术(曲安奈德(TA)辅助和/或内界膜(ILM)剥除)治疗高度近视黄斑裂孔视网膜脱离(MHRD)的疗效。

设计

病例对照研究。

方法

96 例高度近视 MHRD 患者行睫状体平坦部玻璃体切割术联合 2 种辅助手术,随机分为 4 组:A 组,非 TA 辅助 PPV 联合不剥除 ILM;B 组,非 TA 辅助 PPV 联合剥除 ILM;C 组,TA 辅助 PPV 联合不剥除 ILM;D 组,TA 辅助 PPV 联合剥除 ILM。观察视网膜复位、黄斑裂孔闭合及最佳矫正视力。

结果

B 组(84.0%和 44.0%)和 C 组(80.8%和 46.2%)的视网膜复位率和黄斑裂孔闭合率均高于 A 组(73.9%和 17.4%),但 B 组和 C 组之间差异无统计学意义(P>0.05)。A 组和极长眼轴(≥29.0 mm)、“严重”脉络膜视网膜萎缩和后葡萄肿患者的黄斑裂孔闭合率极低。

结论

经睫状体平坦部玻璃体切除术联合 TA 辅助或 ILM 剥除术治疗高度近视性 MHRD 有效。如果剥除 ILM,联合 TA 不会影响闭合率;如果 TA 用于观察玻璃体,则 MHRD 中可能不需要剥除 ILM。极长眼轴、严重脉络膜视网膜萎缩和后葡萄肿的 MHRD 解剖成功率较低。

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