Yonekawa Yoshihiro, Shildkrot Yevgeniy, Eliott Dean
Retina Service, Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, MA 02114, USA.
Ophthalmic Surg Lasers Imaging Retina. 2013 Mar-Apr;44(2):190-2. doi: 10.3928/23258160-20130313-11.
Bilateral diffuse uveal melanocytic proliferation (BDUMP) is a paraneoplastic syndrome characterized by cataract, photoreceptor loss and subretinal fluid overlying patchy areas of retinal pigment epithelium atrophy, and a diffusely thickened choroid with focal nodules. We present the case of a 64-year-old woman with a history of endometrial adenocarcinoma who developed BDUMP with bilateral exudative retinal detachments with inferior peripheral retinal ischemia. This new finding of peripheral nonperfusion expands the spectrum of BDUMP.
双侧弥漫性葡萄膜黑素细胞增生（BDUMP）是一种副肿瘤综合征，其特征为白内障、光感受器丧失、视网膜色素上皮萎缩的片状区域上方出现视网膜下液，以及脉络膜弥漫性增厚并伴有局灶性结节。我们报告了一例64岁有子宫内膜腺癌病史的女性患者，其发生了伴有双侧渗出性视网膜脱离及周边视网膜下部缺血的BDUMP。周边无灌注这一新发现扩展了BDUMP的疾病谱。
