Department of Biochemistry, Genetics and Immunology, University of Vigo, Lagoas-Marcosende, 36310 Vigo, Spain.
Water Res. 2013 May 15;47(8):2742-56. doi: 10.1016/j.watres.2013.02.031. Epub 2013 Mar 4.
This work analyses the mutagenicity of seawater from mussel farms using the Vibrio harveyi mutagenicity test and its relationship with the accumulated pollutants and the development of gonadal neoplasia in mussels. Histological disorders identified as germinoma were observed in the gonad of Mytilus galloprovincialis during the period of study. The prevalence of this pathology is significantly correlated with certain levels of pollutants accumulated in mussels, mainly of PAHs and PCBs, whose toxic equivalents were calculated as EROD induction equivalency. The mutagenicity and toxicity of the water surrounding mussel's farms is clearly correlated with the pollutants accumulated and with the neoplasia prevalence in mussels. Such correlations are corroborated by a multivariate analysis. Our results conclude with the utility of V. harveyi test as an optimal and rapid method in the monitoring of the quality of the water from mussel farms and as a tool to control the risks of pollution on mussel production and its safety for human food.
本研究采用哈维弧菌致突变性试验分析了贝类养殖场海水的致突变性及其与贝类体内污染物积累和性腺肿瘤发生的关系。在研究期间，观察到贻贝性腺中存在被鉴定为生殖细胞瘤的组织紊乱。这种病理学的流行与贻贝中积累的某些污染物水平显著相关，主要是多环芳烃和多氯联苯，其毒性当量计算为 EROD 诱导等效物。贝类养殖场周围水的致突变性和毒性与积累的污染物以及贻贝肿瘤的流行明显相关。多元分析证实了这些相关性。我们的研究结果表明，哈维弧菌试验是贝类养殖场水质监测的一种最佳和快速方法，也是控制贻贝生产污染风险及其作为人类食品安全性的工具。
