Lydiatt D D, Markin R S, Ogren F P
University of Nebraska Medical Center, Omaha.
Ear Nose Throat J. 1990 Mar;69(3):145-9.
Tracheal invasion may occur by direct extension of thyroid carcinoma. Follicular, papillary, mixed follicular and papillary, and poorly differentiated cell types have all been found to cause tracheal invasion. Two cases of tracheal invasion by thyroid carcinomas prompted us to review the literature, although our review revealed little current data on tracheal invasion. We reviewed the records of all patients surgically treated for thyroid carcinoma at the University of Nebraska Medical Center from 1976 through 1987. The results of this review and our review of the literature on tracheal invasion are reported here. We conclude that thyroid carcinomas behave most aggressively in men and older patients. The more poorly differentiated follicular thyroid carcinomas have also been found to behave aggressively. Our findings show that en bloc resections are indicated in certain patients with tracheal invasion.
甲状腺癌可通过直接蔓延侵犯气管。滤泡状癌、乳头状癌、滤泡状和乳头状混合癌以及低分化细胞类型均已被发现可导致气管侵犯。两例甲状腺癌侵犯气管的病例促使我们查阅文献,尽管我们的查阅发现目前关于气管侵犯的资料很少。我们回顾了1976年至1987年在内布拉斯加大学医学中心接受甲状腺癌手术治疗的所有患者的记录。本文报告了此次回顾的结果以及我们对气管侵犯文献的回顾。我们得出结论,甲状腺癌在男性和老年患者中行为最为侵袭性。也已发现分化较差的滤泡状甲状腺癌行为具有侵袭性。我们的研究结果表明,对于某些气管侵犯患者,应进行整块切除。