通过 Ugi 反应和呋喃的开环反应合成新型异喹啉酮和 1,2-二氢异喹啉骨架。
Synthesis of novel isoquinolinone and 1,2-dihydroisoquinoline scaffolds via Ugi reaction and ring opening reaction of furans.
机构信息
Chemical Engineering College, Nanjing University of Science and Technology, Nanjing 210094, People's Republic of China.
出版信息
Mol Divers. 2013 May;17(2):295-305. doi: 10.1007/s11030-013-9434-1. Epub 2013 Mar 20.
PMID:23512552
Abstract
Combining the Ugi reaction with ring opening reaction of furans for the synthesis of novel isoquinolinone and 1,2-dihydroisoquinoline scaffolds has been developed. The isoquinolinone and 1,2-dihydroisoquinoline derivatives with unsaturated carbonyl moiety may open up many opportunities for further functionalizations.
摘要
发展了一种将 Ugi 反应与呋喃的开环反应相结合来合成新型异喹啉酮和 1,2-二氢异喹啉骨架的方法。具有不饱和羰基部分的异喹啉酮和 1,2-二氢异喹啉衍生物可能为进一步的功能化开辟许多机会。
Zotero 插件