Paustovskaia V V
Gig Tr Prof Zabol. 1990(3):7-10.
Basing on experimental toxicity research it was established that, out of 50 atmosphere metal corrosion inhibitors, some 14 per cent were found extremely hazardous, 42 per cent--of high level hazardous, 33 percent--of moderate and 11 per cent--of low hazardous. Relationships were identified between the structure of polymethylene amine salts, azole compounds and carbonic acid, and the way they influence human organism. It was also found that inhibitors exercise a polytropic action in man, the toxicity action being concentrated on oxidation processes, and the inhibitors specifically influence protein, carbohydrate and phosphoric metabolisms, as well as the red blood system. This causes functional and structural disorders of CNS and in the parenchymal organs. Inhibitors are characterized by local and skin-resorption actions, their degree and specific features depending on their chemical structures. 22 MACs of working zone inhibitors are proposed, along with early diagnostic tests and preventive measures.
基于实验毒性研究确定，在50种大气金属腐蚀抑制剂中，约14%被发现具有极高危险性，42%具有高危险性，33%具有中等危险性，11%具有低危险性。已确定聚亚甲基胺盐、唑类化合物和碳酸的结构与其对人体影响方式之间的关系。还发现抑制剂对人体具有多效作用，毒性作用集中于氧化过程，且抑制剂对蛋白质、碳水化合物和磷代谢以及红细胞系统有特定影响。这会导致中枢神经系统和实质器官出现功能和结构紊乱。抑制剂具有局部和经皮吸收作用，其程度和具体特征取决于化学结构。提出了22种工作区抑制剂的职业接触限值，以及早期诊断测试和预防措施。
