Kitporntheranunt Maethaphan
Department of Obstetrics and Gynecology, Faculty of Medicine, Srinakharinwirot University, Nakhon Nayak, Thailand.
J Med Assoc Thai. 2012 Dec;95 Suppl 12:S125-8.
A 28-year-old G2P1 Thai woman presented with severe nausea and vomiting at 12 weeks' gestation. The initial diagnosis was hyperemesis gravidarum. She was clinically euthyroid. Physical examination revealed no thyroid gland enlargement. The serum thyroid stimulating hormone was suppressed while the free thyroxine level was elevated. This patient had a history of hyperthyroidism during her first pregnancy. An anti-thyroid drug was initiated at 16 weeks' gestation and continued throughout her pregnancy. Follow-up thyroid function tests and thyroid antibodies after her first and second gestation were normal. The diagnosis of recurrent gestational thyrotoxicosis was established. There was no need of antithyroid drug treatment in this case. No adverse pregnancy outcomes were reported.
一名28岁、孕2产1的泰国女性在妊娠12周时出现严重恶心和呕吐。初步诊断为妊娠剧吐。她临床甲状腺功能正常。体格检查未发现甲状腺肿大。血清促甲状腺激素被抑制,而游离甲状腺素水平升高。该患者在首次妊娠期间有甲状腺功能亢进病史。在妊娠16周时开始使用抗甲状腺药物,并在整个孕期持续使用。她首次和第二次妊娠后的甲状腺功能检查及甲状腺抗体均正常。确诊为复发性妊娠甲状腺毒症。本例无需抗甲状腺药物治疗。未报告不良妊娠结局。