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嗜铬细胞瘤导致心肌病、缺血性卒中和急性动脉血栓形成:一例病例报告及文献复习

Pheochromocytoma causing cardiomyopathy, ischemic stroke and acute arterial thrombosis: a case report and review of the literature.

作者信息

Vindenes Tine, Crump Natalie, Casenas Ritche, Wood Kelly

机构信息

Department of Internal Medicine, Danbury Hospital, Danbury, CT, USA.

出版信息

Conn Med. 2013 Feb;77(2):95-8.

Abstract

Pheochromocytoma is a rare catecholamine secreting neuroendocrine tumor with an estimated annual incidence of one to four per million and prevalence among hypertensive patients of 0.1 to 0.6%. The symptoms and signs of pheochromocytoma include the classic triad of episodic headache, increased sweating, and palpitations. These are as a result of an uncontrolled release of catecholamines. There exist only a small number of reports of pheochromocytoma simulating hypertrophic obstructive cardiomyopathy, few reports of pheochromocytoma-induced ischemic stroke and only two reported cases with pheochromocytoma-induced arterial thrombosis. We present a case of multiple, rare clinical complications of pheochromocytoma occurring in the same patient and the review of literature of these complications.

摘要

嗜铬细胞瘤是一种罕见的分泌儿茶酚胺的神经内分泌肿瘤,估计年发病率为百万分之一至四,在高血压患者中的患病率为0.1%至0.6%。嗜铬细胞瘤的症状和体征包括发作性头痛、多汗和心悸这一经典三联征。这些是儿茶酚胺不受控制释放的结果。仅有少数关于嗜铬细胞瘤模拟肥厚性梗阻性心肌病的报道,关于嗜铬细胞瘤诱发缺血性卒中的报道较少,仅有两例关于嗜铬细胞瘤诱发动脉血栓形成的报道。我们报告一例同一患者发生的嗜铬细胞瘤多种罕见临床并发症的病例,并对这些并发症的文献进行综述。

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