Hospices Civils de Lyon, Laboratoire de Bactériologie, Centre de Biologie et de Pathologie Est, Lyon, France.
J Clin Microbiol. 2013 Jun;51(6):1970-2. doi: 10.1128/JCM.03377-12. Epub 2013 Mar 20.
Since the introduction of type b Haemophilus influenzae vaccination, noncapsulated H. influenzae has become responsible for most cases of invasive H. influenzae diseases. In our two cases of septic arthritis, we isolated strains with β-lactamase-positive amoxicillin-clavulanate resistance (BLPACR). Thus, the increasing prevalence of BLPACR should be taken into account when empirical therapy is chosen for septic arthritis.
自从乙型流感嗜血杆菌疫苗问世以来,无荚膜流感嗜血杆菌已成为大多数侵袭性流感嗜血杆菌病的病原体。在我们的两例化脓性关节炎中,我们分离出了产β-内酰胺酶且对阿莫西林-克拉维酸耐药的菌株(BLPACR)。因此,在选择化脓性关节炎的经验性治疗时,应考虑到 BLPACR 的流行率不断增加的情况。