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经颅直流电刺激治疗原发性和继发性头痛的临床疗效。

Clinical effectiveness of primary and secondary headache treatment by transcranial direct current stimulation.

机构信息

Department of Neurology, Municipal Center for Medical Rehabilitation of Children with Psychoneurological Disorders Saint Petersburg, Russia ; Neurolife SA Lausanne, Switzerland.

出版信息

Front Neurol. 2013 Mar 21;4:25. doi: 10.3389/fneur.2013.00025. eCollection 2013.

Abstract

The clinical effectiveness of primary and secondary headache treatment by transcranial direct current stimulation (tDCS) with various locations of stimulating electrodes on the scalp was analyzed retrospectively. The results of the treatment were analyzed in 90 patients aged from 19 to 54 years (48 patients had migraine without aura, 32 - frequent episodic tension-type HAs, 10 - chronic tension-type HAs) and in 44 adolescents aged 11-16 years with chronic post-traumatic HAs after a mild head injury. Clinical effectiveness of tDCS with 70-150 μA current for 30-45 min via 6.25 cm(2) stimulating electrodes is comparable to that of modern pharmacological drugs, with no negative side effects. The obtained result has been maintained on average from 5 to 9 months. It has been demonstrated that effectiveness depends on localization of stimulating electrodes used for different types of HAs.

摘要

回顾性分析了经颅直流电刺激(tDCS)以头皮上不同位置的刺激电极治疗原发性和继发性头痛的临床效果。对 90 名年龄在 19 至 54 岁的患者(48 名偏头痛无先兆,32 名频发性紧张型头痛,10 名慢性紧张型头痛)和 44 名 11-16 岁的青少年进行了治疗结果分析,这些青少年在轻度头部受伤后患有慢性创伤后头痛。通过 6.25cm(2)的刺激电极施加 70-150μA 的电流 30-45 分钟,tDCS 的临床效果可与现代药物相媲美,没有任何负面副作用。平均而言,该效果可以维持 5 至 9 个月。结果表明,有效性取决于用于不同类型头痛的刺激电极的定位。

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