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儿童急性中毒:一项二十年的住院患者研究和趋势分析。

Acute poisoning in children under the age of six: a two-decade study of hospital admissions and trends.

机构信息

Department of Anaesthesiology, Kainuu Central Hospital, Kajaani, Finland.

出版信息

Acta Paediatr. 2013 Jul;102(7):e329-33. doi: 10.1111/apa.12238. Epub 2013 Apr 10.

Abstract

AIM

To evaluate the incidence, clinical features and outcome of acute poisoning in children of less than 6 years of age in northern Finland.

METHODS

Children hospitalized with acute poisoning at the Oulu University Hospital between 1991 and 2010 were retrospectively evaluated from hospital records.

RESULTS

There were 334 hospital admissions due to acute poisoning during the study period, with an overall incidence rate of 5.2 per 10 000 per year, decreasing slightly from 6.7 in 1991-1995 to 4.5 in 2006-2010. Mean length of a hospital stay was 1.2 (SD ± 1.26) days. The most common substances ingested were terbutaline (12.3%), benzodiazepines (12.0%) and dishwasher powder (9.3%). Almost half of the patients were admitted to the paediatric intensive care unit, but most only required supportive care. Specific antidotes were administered in 16 cases. Three patients suffered from aspiration pneumonia as a result of ingesting poison, but no children died during the study.

CONCLUSION

Poisoning is a fairly common cause of hospital admission in children under the age of six. In most cases, their clinical condition is good, and they can be discharged after a short surveillance period.

摘要

目的

评估芬兰北部 6 岁以下儿童急性中毒的发生率、临床特征和转归。

方法

对 1991 年至 2010 年期间因急性中毒在奥卢大学医院住院的儿童的病历进行回顾性评估。

结果

研究期间共有 334 例因急性中毒住院,年发病率为 5.2/10000,从 1991-1995 年的 6.7 略有下降至 2006-2010 年的 4.5。平均住院时间为 1.2(SD ± 1.26)天。最常摄入的物质是特布他林(12.3%)、苯二氮䓬类(12.0%)和洗碗机粉(9.3%)。近一半的患者被收入儿科重症监护病房,但大多数只需要支持性治疗。在 16 例中使用了特定的解毒剂。有 3 名患者因摄入毒物而患有吸入性肺炎,但在研究期间没有儿童死亡。

结论

中毒是 6 岁以下儿童住院的常见原因。在大多数情况下,他们的临床状况良好,经过短暂的监测期后即可出院。

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