University of Toronto, Toronto, Ontario, Canada.
J Pediatr. 2013 Jul;163(1):282-4. doi: 10.1016/j.jpeds.2013.02.021. Epub 2013 Mar 20.
It is unclear whether pulmonary arteriovenous malformations (PAVMs) in hereditary hemorrhagic telangiectasia develop later in life or are preformed in childhood. We show that the prevalence of PAVMs in children is similar to that in their parents, providing evidence against de novo PAVM formation in hereditary hemorrhagic telangiectasia.
肺动静脉畸形（PAVMs）在遗传性出血性毛细血管扩张症中是在生命后期发展的，还是在儿童时期就已经存在，目前尚不清楚。我们的研究表明，儿童的 PAVM 患病率与父母相似，这为遗传性出血性毛细血管扩张症中不存在新形成的 PAVM 提供了证据。
