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经腹骶骨阴道固定术中是否使用吊带:成本效益分析。

To sling or not to sling at time of abdominal sacrocolpopexy: a cost-effectiveness analysis.

机构信息

Stanford University School of Medicine, Stanford, California.

出版信息

J Urol. 2013 Oct;190(4):1306-12. doi: 10.1016/j.juro.2013.03.046. Epub 2013 Mar 21.

Abstract

PURPOSE

We compare the cost-effectiveness of 3 strategies for the use of a mid urethral sling to prevent occult stress urinary incontinence in patients undergoing abdominal sacrocolpopexy.

MATERIALS AND METHODS

Using decision analysis modeling we compared cost-effectiveness during a 1-year postoperative period of 3 treatment approaches including 1) abdominal sacrocolpopexy alone with deferred option for mid urethral sling, 2) abdominal sacrocolpopexy with universal concomitant mid urethral sling and 3) preoperative urodynamic study for selective mid urethral sling. Using published data we modeled probabilities of stress urinary incontinence after abdominal sacrocolpopexy with or without mid urethral sling, the predictive value of urodynamic study to detect occult stress urinary incontinence and the likelihood of complications after mid urethral sling. Costs were derived from Medicare 2010 reimbursement rates. The main outcome modeled was incremental cost-effectiveness ratio per quality adjusted life-years gained. In addition to base case analysis, 1-way sensitivity analyses were performed.

RESULTS

In our model, universally performing mid urethral sling at abdominal sacrocolpopexy was the most cost-effective approach with an incremental cost per quality adjusted life-year gained of $2,867 compared to abdominal sacrocolpopexy alone. Preoperative urodynamic study was more costly and less effective than universally performing intraoperative mid urethral sling. The cost-effectiveness of abdominal sacrocolpopexy plus mid urethral sling was robust to sensitivity analysis with a cost-effectiveness ratio consistently below $20,000 per quality adjusted life-year.

CONCLUSIONS

Universal concomitant mid urethral sling is the most cost-effective prophylaxis strategy for occult stress urinary incontinence in women undergoing abdominal sacrocolpopexy. The use of preoperative urodynamic study to guide mid urethral sling placement at abdominal sacrocolpopexy is not cost-effective.

摘要

目的

我们比较了 3 种在腹式子宫骶骨固定术后使用中尿道吊带预防隐匿性压力性尿失禁的策略的成本效益。

材料与方法

我们使用决策分析模型,在术后 1 年的时间内,比较了 3 种治疗方法的成本效益,包括 1)单独进行腹式子宫骶骨固定术,且推迟中尿道吊带的选择;2)腹式子宫骶骨固定术加普遍使用的中尿道吊带;3)术前尿动力学检查,选择性使用中尿道吊带。我们使用已发表的数据,建立了腹式子宫骶骨固定术加或不加中尿道吊带后压力性尿失禁的概率模型、尿动力学检查对隐匿性压力性尿失禁的预测价值,以及中尿道吊带的并发症发生率。费用来源于 Medicare 2010 报销费率。我们主要的模型结果是每增加 1 个质量调整生命年的增量成本效益比。除了基本情况分析,还进行了 1 种敏感性分析。

结果

在我们的模型中,与单独进行腹式子宫骶骨固定术相比,在腹式子宫骶骨固定术中普遍使用中尿道吊带是最具成本效益的方法,每增加 1 个质量调整生命年的增量成本为 2867 美元。术前尿动力学检查比普遍使用术中中尿道吊带更昂贵,效果也更差。腹式子宫骶骨固定术加中尿道吊带的成本效益对敏感性分析具有稳健性,每增加 1 个质量调整生命年的成本效益比始终低于 20000 美元。

结论

在女性进行腹式子宫骶骨固定术时,普遍使用中尿道吊带是预防隐匿性压力性尿失禁最具成本效益的策略。术前尿动力学检查指导在腹式子宫骶骨固定术时放置中尿道吊带并不具有成本效益。

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