Chen Chao-Hsuan, Lin Hung-Lin, Cho Der-Yang
Department of Neurosurgery, China Medical University Hospital; and China Medical University, Taichung, Taiwan.
J Craniofac Surg. 2013 Mar;24(2):468-9. doi: 10.1097/SCS.0b013e318275eb2b.
Primary optic apparatus germ cell tumors are rare. There have been only 6 cases reported in the literature. Although they often disturb the hypothalamus-pituitary-adrenal axis and cause progressive visual loss, the influence of treatment outcomes on hypothalamic autoregulation has never been mentioned. Here, we report a patient with an optic nerve germinoma who presented with reversible visual and hypothalamic dysfunction, and we discuss the possible mechanisms and pathogenesis.